How does Corona Virus (SARC-CoV 2) causes the Pneumonia and multiple organ failure in patient with severe infection ?


Corona virus disease 2019 ( COVID-19) is a new name given to the disease caused by SARC-CoV-2 virus (Corona virus) this disease shows the same symptoms as that of common cold but the real fear arises when the infection goes to lower respiratory tract

Those affected may develop a fever, dry cough, fatigue, and shortness of breath. A sore throat, runny nose or sneezing is less common. While the majority of cases result in mild symptoms

When infection goes to Lower respiratory tract(LRT) it cause fatal disease like PNEUMONIA & MULTI ORAN FAILURE but the known conditions are only seen in people with compromised immunise system, old individual (age> 65) , people with long term medication, Diabetic are high prone to this fatal conditions when they are exposed to corona virus

Cause for pneumonia in corona virus

As the virus particle are mostly genetic and protienecous particle the spikes present on the virus coat have proteinecous messengers which have similarities with SARC viral coat they both have same receptors which are present specifically on Angiotensin converting enzymes 2 receptors (ACE 2) which are present on the lungs.

The viral particle takes the machinery of the host cells due to there activity the immune response initiate that will act in enormous way such that the fluid build up in the alveoli.

Both The lungs will get filled with fluid and waste exudates from the blood due to vasodilation for immune response this causes bacteria a culture and majorly it causes pneumonia

Why does multiple organ failure comes in the picture

When both the lung are filled with fluid the respiration is compromised causing hypoxia (decreased oxygen supply to tissue) which causes decreased O2 saturation level

At this time infection starts spreading all over the body. The bacterial cell flowing through blood activates the macrophages for scavenging the lots of bacteria. Due to this the small clots get formed in the body which decreases the blood Supply to major organs, and also causes the severe septic shock leading to shut down of body organ system turns out to be death of individual

1. The 3 cases explained well to understand how virus works

2. How virus jumps from Animals to Humans

Comment below to get full content

Follow me

Thank you

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s